Antibiotic resistance is a growing public health concern worldwide, with nearly 4.95 million deaths attributed to resistant infections in 2019 alone. This resistance often arises from the overuse and improper disposal of antibiotics, allowing harmful bacteria to survive and spread. Central Michigan University (CMU) is taking significant steps to address this issue through innovative research in wastewater treatment.

A recent study led by Ph.D. student Yasna Mortezaei, alongside professors Dr. Goksel Demirer and Dr. Maggie Williams from the CMU School of Engineering and Technology, investigates how various wastewater treatment processes can help mitigate the spread of antibiotic resistance genes (ARGs) that pose a threat to public health. The research particularly focuses on anaerobic digestion and the role of storage tanks in reducing these harmful genes.

The findings revealed that both the anaerobic digestion process and storage tanks significantly decreased the number of ARGs. Notably, the storage tank emerged as especially effective, suggesting it could further minimize the risks associated with antibiotic resistance in treated wastewater. However, the researchers also identified a concerning trend: while intracellular ARGs decreased during anaerobic digestion, the levels of cell-free ARGs increased. These cell-free genes are particularly alarming because they can spread more easily in the environment and can persist for extended periods.

Mortezaei emphasized the significance of their research, stating, “Our research provides valuable information that could help limit the spread of antibiotic resistance in wastewater systems, ultimately protecting both public health and the environment.”

This study highlights CMU's commitment to addressing real-world environmental challenges and offers students the opportunity to engage in impactful research. Those considering a future at CMU can participate in innovative projects focusing on issues like antibiotic resistance, gaining hands-on experience in tackling complex global problems through teamwork in microbiology and environmental studies.

As CMU continues to lead in vital scientific research, students can anticipate involvement in initiatives aimed at developing sustainable solutions for pollution and health protection, reinforcing the university's role in advancing public health and environmental safety.